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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FOXD4
All Species:
0
Human Site:
T249
Identified Species:
0
UniProt:
Q12950
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12950
NP_997188.2
439
47251
T249
V
P
G
A
Y
P
N
T
G
P
G
R
R
P
Y
Chimpanzee
Pan troglodytes
NP_001009014
413
45421
L224
L
S
A
A
H
A
A
L
H
N
P
R
P
G
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q60688
444
48029
A248
N
L
A
A
H
P
A
A
P
P
R
S
H
P
C
Rat
Rattus norvegicus
Q63245
101
11924
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516678
728
77542
P355
P
G
L
L
L
Y
P
P
G
P
G
P
S
P
C
Chicken
Gallus gallus
P79772
394
40977
R209
D
N
G
S
F
L
R
R
R
K
R
F
K
R
H
Frog
Xenopus laevis
Q9DEN4
371
40000
R192
R
R
R
K
R
F
K
R
Q
Q
Q
D
S
L
R
Zebra Danio
Brachydanio rerio
NP_571365
371
40457
F192
F
L
R
R
R
K
R
F
K
R
H
Q
P
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02361
456
49036
F220
V
H
F
N
V
P
N
F
N
G
S
R
E
F
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496411
333
37274
C154
K
L
T
L
S
E
I
C
E
F
I
I
N
K
F
Sea Urchin
Strong. purpuratus
XP_001188749
401
43606
Q217
R
R
K
R
Y
K
R
Q
Q
P
D
F
F
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.6
N.A.
N.A.
N.A.
48.6
20.5
N.A.
33
38.2
34.8
32.7
N.A.
30.9
N.A.
31.2
34.8
Protein Similarity:
100
83.1
N.A.
N.A.
N.A.
55.6
21.6
N.A.
41.4
46.7
46.4
45.3
N.A.
44
N.A.
43.2
44.8
P-Site Identity:
100
13.3
N.A.
N.A.
N.A.
26.6
0
N.A.
26.6
6.6
0
0
N.A.
26.6
N.A.
0
13.3
P-Site Similarity:
100
26.6
N.A.
N.A.
N.A.
33.3
0
N.A.
26.6
33.3
0
6.6
N.A.
26.6
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
28
0
10
19
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
19
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
10
10
0
10
10
% D
% Glu:
0
0
0
0
0
10
0
0
10
0
0
0
10
0
10
% E
% Phe:
10
0
10
0
10
10
0
19
0
10
0
19
10
10
10
% F
% Gly:
0
10
19
0
0
0
0
0
19
10
19
0
0
10
0
% G
% His:
0
10
0
0
19
0
0
0
10
0
10
0
10
0
10
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
10
10
0
0
10
% I
% Lys:
10
0
10
10
0
19
10
0
10
10
0
0
10
10
0
% K
% Leu:
10
28
10
19
10
10
0
10
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
10
0
0
19
0
10
10
0
0
10
0
0
% N
% Pro:
10
10
0
0
0
28
10
10
10
37
10
10
19
28
10
% P
% Gln:
0
0
0
0
0
0
0
10
19
10
10
10
0
0
0
% Q
% Arg:
19
19
19
19
19
0
28
19
10
10
19
28
10
19
10
% R
% Ser:
0
10
0
10
10
0
0
0
0
0
10
10
19
0
0
% S
% Thr:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
19
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
19
10
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _